Clinical, Epidemiological and Microbiological Profile of A Potentially Pathogenic Environmental Saprophyte, Burkholderia pseudomallei; at A Tertiary Care Hospital in Coastal India

Melioidosis is a severe systemic infectious disease caused by Burkholderia pseudomallei, gram-negative bacillus with bipolar staining. It an environmental saprophyte endemic to Southeast Asia and Northern Australia. The can have varying manifestations. This retrospective study of the clinical microbiological profile culture-proven cases melioidosis who presented tertiary care hospital in Coastal Karnataka between January 2018 December 2020. epidemiological, demographic, laboratory characteristics were studied analyzed. A total 27 seen during period. All patients from western coastal areas India. Fever was most common presenting complaint. Analysis manifestations showed 11 (40.74%) bacteremia. Pneumonia primary presentation (40.74%). 9 (33.3%) had abscess some part body on presentation. Secondary foci 5 (18.5%) patients. prominent risk factors history type 2 diabetes mellitus, age >40 years, alcoholism smoking. 13 (48.15%) started treatment regimen for melioidosis. Only 8 (29.63%) prescribed eradication regimen. One case which inadequately treated came back reactivation Varied makes specific diagnosis difficult. Due high mortality morbidity rate, early prompt management warranted, this requires vigilance intensive workup. Lack adherence protocol lead reactivation.